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Changes in Blood Cell Deformability in Chorea-Acanthocytosis and Effects of Treatment With Dasatinib or Lithium

Misshaped red blood cells (RBCs), characterized by thorn-like protrusions known as acanthocytes, are a key diagnostic feature in Chorea-Acanthocytosis (ChAc), a rare neurodegenerative disorder. The altered RBC morphology likely influences their biomechanical properties which are crucial for the cell...

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Detalles Bibliográficos
Autores principales: Reichel, Felix, Kräter, Martin, Peikert, Kevin, Glaß, Hannes, Rosendahl, Philipp, Herbig, Maik, Rivera Prieto, Alejandro, Kihm, Alexander, Bosman, Giel, Kaestner, Lars, Hermann, Andreas, Guck, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013823/
https://www.ncbi.nlm.nih.gov/pubmed/35444561
http://dx.doi.org/10.3389/fphys.2022.852946