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Clinicopathological Significance of PTEN Expression and Its Prognostic Effect in Colorectal Adenocarcinoma Patients

BACKGROUND & OBJECTIVE: Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene located at chromosome 10. PTEN is a regulator of the PI3K/AKT signaling pathway that inhibits cell proliferation and promotes apoptosis. PTEN loss of function occurs in a spectrum of cancers, including color...

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Detalles Bibliográficos
Autores principales: Mirzapour Abbas Abadi, Zohreh, Samiee Rad, Fatemeh, Hamedi Asl, Dariush, Rahmani, Babak, Soleimani Dodaran, Mahmood, Peimani, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Pathology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013865/
https://www.ncbi.nlm.nih.gov/pubmed/35463728
http://dx.doi.org/10.30699/IJP.2021.531779.2653