Platelet-Depletion of Whole Blood Reveals That Platelets Potentiate the Release of IL-8 From Leukocytes Into Plasma in a Thrombin-Dependent Manner

OBJECTIVE: In a recent study, we found an elevated level of interleukin 8 (IL-8) in response to bacterial incubation in thrombin-sufficient human whole blood anticoagulated by the fibrin polymerization blocking peptide GPRP. Whether thrombin directly activated leukocytes or mediated the release via...

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Detalles Bibliográficos
Autores principales: Quach, Huy Quang, Johnson, Christina, Ekholt, Karin, Islam, Rakibul, Mollnes, Tom Eirik, Nilsson, Per H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013889/
https://www.ncbi.nlm.nih.gov/pubmed/35444648
http://dx.doi.org/10.3389/fimmu.2022.865386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013889/
https://www.ncbi.nlm.nih.gov/pubmed/35444648
http://dx.doi.org/10.3389/fimmu.2022.865386

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