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Platelet-Depletion of Whole Blood Reveals That Platelets Potentiate the Release of IL-8 From Leukocytes Into Plasma in a Thrombin-Dependent Manner
OBJECTIVE: In a recent study, we found an elevated level of interleukin 8 (IL-8) in response to bacterial incubation in thrombin-sufficient human whole blood anticoagulated by the fibrin polymerization blocking peptide GPRP. Whether thrombin directly activated leukocytes or mediated the release via...
Autores principales: | Quach, Huy Quang, Johnson, Christina, Ekholt, Karin, Islam, Rakibul, Mollnes, Tom Eirik, Nilsson, Per H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013889/ https://www.ncbi.nlm.nih.gov/pubmed/35444648 http://dx.doi.org/10.3389/fimmu.2022.865386 |
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