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Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids

Gypenosides (GPs), obtained from Gynostemma pentaphyllum (Thunb.) Makino, have been traditionally prescribed to treat metabolic disorders in Asians. This study assessed whether GPs could prevent lithogenic diet (LD)-induced cholesterol gallstone (CG) formation and enhance CG dissolution in mice. Gal...

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Detalles Bibliográficos
Autores principales: Zhuang, Qian, Cheng, Jinnian, Xia, Jie, Ning, Min, Wu, Shan, Shen, Shuang, Shi, Yan, Huang, Dan, Dong, Zhixia, Wan, Xinjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013900/
https://www.ncbi.nlm.nih.gov/pubmed/35445045
http://dx.doi.org/10.3389/fmed.2022.818144