Expression of Human Interleukin 8 in Mice Alters Their Natural Behaviors

OBJECTIVE: To examine the effects of human interleukin (IL) 8 expression on mouse behavior. METHODS: A mouse line expressing human IL8 in the intervertebral discs (IVD) and cartilaginous tissues (hIL8(+)) was generated. Mouse spontaneous behaviors, including locomotion, climbing, rearing, grooming,...

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Detalles Bibliográficos
Autores principales: Tian, Zuozhen, Shofer, Frances S, Sandroni, Alec Z, Zhao, Lan, Scanzello, Carla R, Zhang, Yejia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013918/
https://www.ncbi.nlm.nih.gov/pubmed/35444450
http://dx.doi.org/10.2147/JIR.S355669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013918/
https://www.ncbi.nlm.nih.gov/pubmed/35444450
http://dx.doi.org/10.2147/JIR.S355669

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