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Expression of Human Interleukin 8 in Mice Alters Their Natural Behaviors
OBJECTIVE: To examine the effects of human interleukin (IL) 8 expression on mouse behavior. METHODS: A mouse line expressing human IL8 in the intervertebral discs (IVD) and cartilaginous tissues (hIL8(+)) was generated. Mouse spontaneous behaviors, including locomotion, climbing, rearing, grooming,...
Autores principales: | Tian, Zuozhen, Shofer, Frances S, Sandroni, Alec Z, Zhao, Lan, Scanzello, Carla R, Zhang, Yejia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013918/ https://www.ncbi.nlm.nih.gov/pubmed/35444450 http://dx.doi.org/10.2147/JIR.S355669 |
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