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Pulsed-Ultrasound Irradiation Induces the Production of Itaconate and Attenuates Inflammatory Responses in Macrophages

BACKGROUND: Itaconate is a key metabolite in the innate immune system and exerts strong anti-inflammatory effects in macrophages. For the production of itaconate in macrophages, immune-responsive gene 1 (IRG1) is an imperative enzyme, and activating the IRG1-itaconate pathway is reported to alleviat...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Atomu, Maeshige, Noriaki, Ma, Xiaoqi, Uemura, Mikiko, Noguchi, Hikari, Matsuda, Mami, Nishimura, Yuya, Hasunuma, Tomohisa, Kondo, Hiroyo, Fujino, Hidemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013924/
https://www.ncbi.nlm.nih.gov/pubmed/35444446
http://dx.doi.org/10.2147/JIR.S361609