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Droplet-Microfluidic-Based Promoter Engineering and Expression Fine-Tuning for Improved Erythromycin Production in Saccharopolyspora erythraea NRRL 23338

Erythromycin is a clinically important drug produced by the rare actinomycete Saccharopolyspora erythraea. In the wide-type erythromycin producer S. erythraea NRRL 23338, there is a lack of systematical method for promoter engineering as well as a well-characterized promoter panel for comprehensive...

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Detalles Bibliográficos
Autores principales: Yun, Kaiyue, Zhang, Yue, Li, Shixin, Wang, Yan, Tu, Ran, Liu, Hao, Wang, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013967/
https://www.ncbi.nlm.nih.gov/pubmed/35445005
http://dx.doi.org/10.3389/fbioe.2022.864977