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Droplet-Microfluidic-Based Promoter Engineering and Expression Fine-Tuning for Improved Erythromycin Production in Saccharopolyspora erythraea NRRL 23338
Erythromycin is a clinically important drug produced by the rare actinomycete Saccharopolyspora erythraea. In the wide-type erythromycin producer S. erythraea NRRL 23338, there is a lack of systematical method for promoter engineering as well as a well-characterized promoter panel for comprehensive...
Autores principales: | Yun, Kaiyue, Zhang, Yue, Li, Shixin, Wang, Yan, Tu, Ran, Liu, Hao, Wang, Meng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013967/ https://www.ncbi.nlm.nih.gov/pubmed/35445005 http://dx.doi.org/10.3389/fbioe.2022.864977 |
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