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Cancer stem-like cells evade CD8(+)CD103(+) tumor-resident memory T (T(RM)) lymphocytes by initiating an epithelial-to-mesenchymal transition program in a human lung tumor model

BACKGROUND: Cancer stem cells (CSC) define a population of rare malignant cells endowed with ‘stemness’ properties, such as self-renewing, multipotency and tumorigenicity. They are responsible for tumor initiation and progression, and could be associated with resistance to immunotherapies by negativ...

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Detalles Bibliográficos
Autores principales: Corgnac, Stéphanie, Damei, Isabelle, Gros, Gwendoline, Caidi, Aziza, Terry, Stéphane, Chouaib, Salem, Deloger, Marc, Mami-Chouaib, Fathia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014106/
https://www.ncbi.nlm.nih.gov/pubmed/35418483
http://dx.doi.org/10.1136/jitc-2022-004527