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Cancer stem-like cells evade CD8(+)CD103(+) tumor-resident memory T (T(RM)) lymphocytes by initiating an epithelial-to-mesenchymal transition program in a human lung tumor model
BACKGROUND: Cancer stem cells (CSC) define a population of rare malignant cells endowed with ‘stemness’ properties, such as self-renewing, multipotency and tumorigenicity. They are responsible for tumor initiation and progression, and could be associated with resistance to immunotherapies by negativ...
Autores principales: | Corgnac, Stéphanie, Damei, Isabelle, Gros, Gwendoline, Caidi, Aziza, Terry, Stéphane, Chouaib, Salem, Deloger, Marc, Mami-Chouaib, Fathia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014106/ https://www.ncbi.nlm.nih.gov/pubmed/35418483 http://dx.doi.org/10.1136/jitc-2022-004527 |
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