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Population differentiation of polygenic score predictions under stabilizing selection
Given the many small-effect loci uncovered by genome-wide association studies (GWAS), polygenic scores have become central to genomic medicine, and have found application in diverse settings including evolutionary studies of adaptation. Despite their promise, polygenic scores have been found to suff...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014188/ https://www.ncbi.nlm.nih.gov/pubmed/35430887 http://dx.doi.org/10.1098/rstb.2020.0416 |