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How HLA diversity is apportioned: influence of selection and relevance to transplantation

In his 1972 paper ‘The apportionment of human diversity’, Lewontin showed that, when averaged over loci, genetic diversity is predominantly attributable to differences among individuals within populations. However, selection can alter the apportionment of diversity of specific genes or genomic regio...

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Detalles Bibliográficos
Autores principales: Maróstica, André Silva, Nunes, Kelly, Castelli, Erick C., Silva, Nayane S. B., Weir, Bruce S., Goudet, Jérôme, Meyer, Diogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014195/
https://www.ncbi.nlm.nih.gov/pubmed/35430892
http://dx.doi.org/10.1098/rstb.2020.0420