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How HLA diversity is apportioned: influence of selection and relevance to transplantation
In his 1972 paper ‘The apportionment of human diversity’, Lewontin showed that, when averaged over loci, genetic diversity is predominantly attributable to differences among individuals within populations. However, selection can alter the apportionment of diversity of specific genes or genomic regio...
Autores principales: | Maróstica, André Silva, Nunes, Kelly, Castelli, Erick C., Silva, Nayane S. B., Weir, Bruce S., Goudet, Jérôme, Meyer, Diogo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014195/ https://www.ncbi.nlm.nih.gov/pubmed/35430892 http://dx.doi.org/10.1098/rstb.2020.0420 |
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