The Search for Cyclooxygenase-2 (COX-2) Inhibitors for the Treatment of Inflammation Disease: An in-silico Study

PURPOSE: Cyclooxygenase (COX-2) has been validated as a molecular target for treating inflammatory diseases. The present work was performed to identify potential COX-2 inhibitors by employing pharmacophore modeling. METHODS: The pharmacophore features consisted of seven features, ie, three hydrophob...

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Detalles Bibliográficos
Autores principales: Ruslin, Ruslin, Yamin, Yamin, Kasmawati, Henny, Mangrura, Samuel, Kadidae, Laode, Alroem, Armid, Arba, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014226/
https://www.ncbi.nlm.nih.gov/pubmed/35444425
http://dx.doi.org/10.2147/JMDH.S359429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014226/
https://www.ncbi.nlm.nih.gov/pubmed/35444425
http://dx.doi.org/10.2147/JMDH.S359429

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