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Signaling Pathways That Mediate Alveolar Macrophage Activation by Surfactant Protein A and IL-4
Activation of tissue repair program in macrophages requires the integration of IL-4/IL-13 cytokines and tissue-specific signals. In the lung, surfactant protein A (SP-A) is a tissue factor that amplifies IL-4Rα-dependent alternative activation and proliferation of alveolar macrophages (AMs) through...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014242/ https://www.ncbi.nlm.nih.gov/pubmed/35444643 http://dx.doi.org/10.3389/fimmu.2022.860262 |