Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner

Upon intracellular recognition of viral RNA, RIG-I-like proteins interact with MAVS at peroxisomes and mitochondria, inducing its oligomerization and the downstream production of direct antiviral effectors. The human cytomegalovirus (HCMV) is able to specifically evade this antiviral response, via i...

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Detalles Bibliográficos
Autores principales: Ferreira, Ana Rita, Gouveia, Ana, Magalhães, Ana Cristina, Valença, Isabel, Marques, Mariana, Kagan, Jonathan C., Ribeiro, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014249/
https://www.ncbi.nlm.nih.gov/pubmed/35445031
http://dx.doi.org/10.3389/fcell.2022.871977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014249/
https://www.ncbi.nlm.nih.gov/pubmed/35445031
http://dx.doi.org/10.3389/fcell.2022.871977

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