Engineered RBCs Encapsulating Antigen Induce Multi-Modal Antigen-Specific Tolerance and Protect Against Type 1 Diabetes

Antigen-specific therapies that suppress autoreactive T cells without inducing systemic immunosuppression are a much-needed treatment for autoimmune diseases, yet effective strategies remain elusive. We describe a microfluidic Cell Squeeze(®) technology to engineer red blood cells (RBCs) encapsulati...

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Detalles Bibliográficos
Autores principales: Raposo, Colin J., Cserny, Judith D., Serena, Gloria, Chow, Jonathan N., Cho, Patricia, Liu, Hanyang, Kotler, David, Sharei, Armon, Bernstein, Howard, John, Shinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014265/
https://www.ncbi.nlm.nih.gov/pubmed/35444659
http://dx.doi.org/10.3389/fimmu.2022.869669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014265/
https://www.ncbi.nlm.nih.gov/pubmed/35444659
http://dx.doi.org/10.3389/fimmu.2022.869669

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