AMG853, A Bispecific Prostaglandin D(2) Receptor 1 and 2 Antagonist, Dampens Basophil Activation and Related Lupus-Like Nephritis Activity in Lyn-Deficient Mice

Systemic lupus erythematosus is a complex autoimmune disease during which patients develop autoantibodies raised against nuclear antigens. During the course of the disease, by accumulating in secondary lymphoid organs (SLOs), basophils support autoreactive plasma cells to amplify autoantibody produc...

Descripción completa

Detalles Bibliográficos
Autores principales: Pellefigues, Christophe, Tchen, John, Saji, Chaimae, Lamri, Yasmine, Charles, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014266/
https://www.ncbi.nlm.nih.gov/pubmed/35444641
http://dx.doi.org/10.3389/fimmu.2022.824686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014266/
https://www.ncbi.nlm.nih.gov/pubmed/35444641
http://dx.doi.org/10.3389/fimmu.2022.824686

Ejemplares similares