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Genetic and Functional Analyses of Archaeal ATP-Dependent RNA Ligase in C/D Box sRNA Circularization and Ribosomal RNA Processing

RNA ligases play important roles in repairing and circularizing RNAs post-transcriptionally. In this study, we generated an allelic knockout of ATP-dependent RNA ligase (Rnl) in the hyperthermophilic archaeon Thermococcus kodakarensis to identify its biological targets. A comparative analysis of cir...

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Detalles Bibliográficos
Autores principales: Liu, Yancheng, Takagi, Yuko, Sugijanto, Milyadi, Nguyen, Kieu Duong My, Hirata, Akira, Hori, Hiroyuki, Ho, C. Kiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014305/
https://www.ncbi.nlm.nih.gov/pubmed/35445080
http://dx.doi.org/10.3389/fmolb.2022.811548