Cargando…

Synergistic combination of PMBA and 5-fluorouracil (5-FU) in targeting mutant KRAS in 2D and 3D colorectal cancer cells

β-Boswellic acid (β-BA), a potent NF-kB signaling pathway inhibitor, has shown synergistic anti-cancerous activity (NCT03149081, NCT00243022 and NCT02977936) in various clinical trials as complementary therapies. The study has been conducted to investigate the effect and efficacy of 2-pyridin-4-yl m...

Descripción completa

Detalles Bibliográficos
Autores principales: Qayum, Arem, Magotra, Asmita, Shah, Syed Mohmad, Nandi, Utpal, Sharma, P.R., Shah, Bhahwal Ali, Singh, Shashank Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014391/
https://www.ncbi.nlm.nih.gov/pubmed/35445157
http://dx.doi.org/10.1016/j.heliyon.2022.e09103