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A Murine Ommaya Xenograft Model to Study Direct-Targeted Therapy of Leptomeningeal Disease

Leptomeningeal disease (LMD) is an uncommon type of central nervous system (CNS) metastasis to the cerebral spinal fluid (CSF). The most common cancers that cause LMD are breast and lung cancers and melanoma. Patients diagnosed with LMD have a very poor prognosis and generally survive for only a few...

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Detalles Bibliográficos
Autores principales: Law, Vincent, Baldwin, Margi, Ramamoorthi, Ganesan, Kodumudi, Krithika, Tran, Nam, Smalley, Inna, Duckett, Derek, Kalinski, Pawel, Czerniecki, Brian, Smalley, Keiran S. M., Forsyth, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014476/
https://www.ncbi.nlm.nih.gov/pubmed/33586709
http://dx.doi.org/10.3791/62033