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Impact of klotho on the expression of SRGAP2a in podocytes in diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN) is the major cause of kidney failure, and glomerular podocytes play critical roles in the pathogenesis of DN by maintaining the glomerular structure and filtration barrier. Klotho and Slit-Robo GTP activating protein 2a (SRGAP2a) have been indicated to play prot...

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Detalles Bibliográficos
Autores principales: Jin, Donghua, Jia, Miao, Xie, Yuxian, Lin, Lihua, Qiu, Hong, Lu, Guoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014571/
https://www.ncbi.nlm.nih.gov/pubmed/35436879
http://dx.doi.org/10.1186/s12882-022-02765-z