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Rapamycin improves the quality and developmental competence of mice oocytes by promoting DNA damage repair during in vitro maturation
BACKGROUND: Increasing evidence has shown that the mammalian target of rapamycin (mTOR) pathway plays a critical role in oocyte meiosis and embryonic development, however, previous studies reporting the effects of rapamycin on oocyte IVM showed different or even opposite results, and the specific me...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014618/ https://www.ncbi.nlm.nih.gov/pubmed/35436937 http://dx.doi.org/10.1186/s12958-022-00943-0 |