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Hydroxamate and thiosemicarbazone: Two highly promising scaffolds for the development of SARS-CoV-2 antivirals

The emerging COVID-19 pandemic generated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has severely threatened human health. The main protease (M(pro)) of SARS-CoV-2 is promising target for antiviral drugs, which plays a vital role for viral duplication. Development of the inhibito...

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Detalles Bibliográficos
Autores principales: Xu, Yin-Sui, Chigan, Jia-Zhu, Li, Jia-Qi, Ding, Huan-Huan, Sun, Le-Yun, Liu, Lu, Hu, Zhenxin, Yang, Ke-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014651/
https://www.ncbi.nlm.nih.gov/pubmed/35462235
http://dx.doi.org/10.1016/j.bioorg.2022.105799