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Preclinical in vivo longitudinal assessment of KG207-M as a disease-modifying Alzheimer’s disease therapeutic

In vivo biomarker abnormalities provide measures to monitor therapeutic interventions targeting amyloid-β pathology as well as its effects on downstream processes associated with Alzheimer’s disease pathophysiology. Here, we applied an in vivo longitudinal study design combined with imaging and cere...

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Detalles Bibliográficos
Autores principales: Kang, Min Su, Shin, Monica, Ottoy, Julie, Aliaga, Arturo Aliaga, Mathotaarachchi, Sulantha, Quispialaya, Kely, Pascoal, Tharick A, Collins, D Louis, Chakravarty, M. Mallar, Mathieu, Axel, Sandelius, Åsa, Blennow, Kaj, Zetterberg, Henrik, Massarweh, Gassan, Soucy, Jean-Paul, Cuello, A Claudio, Gauthier, Serge, Waterston, Michael, Yoganathan, Nathan, Lessard, Etienne, Haqqani, Arsalan, Rennie, Kerry, Stanimirovic, Danica, Chakravarthy, Balu, Rosa-Neto, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014686/
https://www.ncbi.nlm.nih.gov/pubmed/34378436
http://dx.doi.org/10.1177/0271678X211035625