Challenges of modelling approaches for network meta-analysis of time-to-event outcomes in the presence of non-proportional hazards to aid decision making: Application to a melanoma network

BACKGROUND: Synthesis of clinical effectiveness from multiple trials is a well-established component of decision-making. Time-to-event outcomes are often synthesised using the Cox proportional hazards model assuming a constant hazard ratio over time. However, with an increasing proportion of trials...

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Detalles Bibliográficos
Autores principales: Freeman, Suzanne C, Cooper, Nicola J, Sutton, Alex J, Crowther, Michael J, Carpenter, James R, Hawkins, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014691/
https://www.ncbi.nlm.nih.gov/pubmed/35044255
http://dx.doi.org/10.1177/09622802211070253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014691/
https://www.ncbi.nlm.nih.gov/pubmed/35044255
http://dx.doi.org/10.1177/09622802211070253

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