Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies

Several studies have confirmed the α-synuclein real-time quaking-induced conversion (RT-QuIC) assay to have high sensitivity and specificity for Parkinson’s disease. However, whether the assay can be used as a robust, quantitative measure to monitor disease progression, stratify different synucleino...

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Detalles Bibliográficos
Autores principales: Poggiolini, Ilaria, Gupta, Vandana, Lawton, Michael, Lee, Seoyun, El-Turabi, Aadil, Querejeta-Coma, Agustin, Trenkwalder, Claudia, Sixel-Döring, Friederike, Foubert-Samier, Alexandra, Pavy-Le Traon, Anne, Plazzi, Giuseppe, Biscarini, Francesco, Montplaisir, Jacques, Gagnon, Jean-François, Postuma, Ronald B, Antelmi, Elena, Meissner, Wassilios G, Mollenhauer, Brit, Ben-Shlomo, Yoav, Hu, Michele T, Parkkinen, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014737/
https://www.ncbi.nlm.nih.gov/pubmed/34894214
http://dx.doi.org/10.1093/brain/awab431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014737/
https://www.ncbi.nlm.nih.gov/pubmed/34894214
http://dx.doi.org/10.1093/brain/awab431

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