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Sequential immunizations confer cross-protection against variants of SARS-CoV-2, including Omicron in Rhesus macaques

Variants of concern (VOCs) like Delta and Omicron, harbor a high number of mutations, which aid these viruses in escaping a majority of known SARS-CoV-2 neutralizing antibodies (NAbs). In this study, Rhesus macaques immunized with 2-dose inactivated vaccines (Coronavac) were boosted with an addition...

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Detalles Bibliográficos
Autores principales: Deng, Wei, Lv, Qi, Li, Fengdi, Liu, Jiangning, Song, Zhiqi, Qi, Feifei, Wei, Qiang, Yu, Pin, Liu, Mingya, Zhou, Shasha, Zhang, Yaqing, Gao, Hong, Wang, Nan, Jia, Zijing, Gao, Kai, Liu, Jiayi, Xiao, Chong, Shang, Haiquan, Wang, Xiangxi, Bao, Linlin, Qin, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014776/
https://www.ncbi.nlm.nih.gov/pubmed/35436986
http://dx.doi.org/10.1038/s41392-022-00979-z