Cargando…

Development of Novel (191)Pt-Labeled Hoechst33258: (191)Pt Is More Suitable than (111)In for Targeting DNA

[Image: see text] This study aims to establish new labeling methods for no-carrier-added radio-Pt ((191)Pt) and to evaluate the in vitro properties of (191)Pt-labeled agents compared with those of agents labeled with the common emitter (111)In. (191)Pt was complexed with the DNA-targeting dye Hoechs...

Descripción completa

Detalles Bibliográficos
Autores principales: Obata, Honoka, Tsuji, Atsushi B., Kumata, Katsushi, Sudo, Hitomi, Minegishi, Katsuyuki, Nagatsu, Kotaro, Takakura, Hideo, Ogawa, Mikako, Kurimasa, Akihiro, Zhang, Ming-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014856/
https://www.ncbi.nlm.nih.gov/pubmed/35358392
http://dx.doi.org/10.1021/acs.jmedchem.1c02209