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Vault RNA1–1 riboregulates the autophagic function of p62 by binding to lysine 7 and arginine 21, both of which are critical for p62 oligomerization

Cellular processes can be regulated at multiple levels, including transcriptional, post-transcriptional, and post-translational mechanisms. We have recently shown that the small, noncoding vault RNA1–1 negatively riboregulates p62 oligomerization in selective autophagy through direct interaction wit...

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Detalles Bibliográficos
Autores principales: Büscher, Magdalena, Horos, Rastislav, Huppertz, Ina, Haubrich, Kevin, Dobrev, Nikolay, Baudin, Florence, Hennig, Janosch, Hentze, Matthias W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014876/
https://www.ncbi.nlm.nih.gov/pubmed/35210358
http://dx.doi.org/10.1261/rna.079129.122