Cargando…
Vault RNA1–1 riboregulates the autophagic function of p62 by binding to lysine 7 and arginine 21, both of which are critical for p62 oligomerization
Cellular processes can be regulated at multiple levels, including transcriptional, post-transcriptional, and post-translational mechanisms. We have recently shown that the small, noncoding vault RNA1–1 negatively riboregulates p62 oligomerization in selective autophagy through direct interaction wit...
Autores principales: | Büscher, Magdalena, Horos, Rastislav, Huppertz, Ina, Haubrich, Kevin, Dobrev, Nikolay, Baudin, Florence, Hennig, Janosch, Hentze, Matthias W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014876/ https://www.ncbi.nlm.nih.gov/pubmed/35210358 http://dx.doi.org/10.1261/rna.079129.122 |
Ejemplares similares
-
‘High vault-age’: non-coding RNA control of autophagy
por: Büscher, Magdalena, et al.
Publicado: (2020) -
Autophagic Regulation of p62 is Critical for Cancer Therapy
por: Islam, Md. Ariful, et al.
Publicado: (2018) -
Advantages and Limitations of Different p62-Based Assays for Estimating Autophagic Activity in Drosophila
por: Pircs, Karolina, et al.
Publicado: (2012) -
Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation
por: Sun, Daxiao, et al.
Publicado: (2018) -
Autophagic receptor p62 protects against glycation‐derived toxicity and enhances viability
por: Aragonès, Gemma, et al.
Publicado: (2020)