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Precise gene models using long-read sequencing reveal a unique poly(A) signal in Giardia lamblia

During pre-mRNA processing, the poly(A) signal is recognized by a protein complex that ensures precise cleavage and polyadenylation of the nascent transcript. The location of this cleavage event establishes the length and sequence of the 3′ UTR of an mRNA, thus determining much of its post-transcrip...

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Detalles Bibliográficos
Autores principales: Bilodeau, Danielle Y., Sheridan, Ryan M., Balan, Balu, Jex, Aaron R., Rissland, Olivia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014877/
https://www.ncbi.nlm.nih.gov/pubmed/35110372
http://dx.doi.org/10.1261/rna.078793.121