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Precise gene models using long-read sequencing reveal a unique poly(A) signal in Giardia lamblia
During pre-mRNA processing, the poly(A) signal is recognized by a protein complex that ensures precise cleavage and polyadenylation of the nascent transcript. The location of this cleavage event establishes the length and sequence of the 3′ UTR of an mRNA, thus determining much of its post-transcrip...
Autores principales: | Bilodeau, Danielle Y., Sheridan, Ryan M., Balan, Balu, Jex, Aaron R., Rissland, Olivia S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014877/ https://www.ncbi.nlm.nih.gov/pubmed/35110372 http://dx.doi.org/10.1261/rna.078793.121 |
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