Effects of transgene insertion loci and copy number on Dnmt3L gene silencing through antisense transgene-derived PIWI-interacting RNAs

PIWI-interacting RNAs (piRNAs), which are germ cell-specific small RNAs, are essential for spermatogenesis. In fetal mouse germ cells, piRNAs are synthesized from sense and antisense RNAs of transposable element sequences for retrotransposon silencing. In a previous study, we reported that transgeni...

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Detalles Bibliográficos
Autores principales: Lee, SePil, Kuramochi-Miyagawa, Satomi, Nagamori, Ippei, Nakano, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014882/
https://www.ncbi.nlm.nih.gov/pubmed/35145000
http://dx.doi.org/10.1261/rna.078905.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014882/
https://www.ncbi.nlm.nih.gov/pubmed/35145000
http://dx.doi.org/10.1261/rna.078905.121

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