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The efficacy of a 2,4-diaminoquinazoline compound as an intranasal vaccine adjuvant to protect against influenza A virus infection in vivo

Adjuvants are substances added to vaccines to enhance antigen-specific immune responses or to protect antigens from rapid elimination. As pattern recognition receptors, Toll-like receptors 7 (TLR7) and 8 (TLR8) activate the innate immune system by sensing endosomal single-stranded RNA of RNA viruses...

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Detalles Bibliográficos
Autores principales: Noh, Kyungseob, Jeong, Eun Ju, An, Timothy, Shin, Jin Soo, Kim, Hyejin, Han, Soo Bong, Kim, Meehyein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Microbiological Society of Korea 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014970/
https://www.ncbi.nlm.nih.gov/pubmed/35437625
http://dx.doi.org/10.1007/s12275-022-1661-7