Down-Regulation of miR-138 Alleviates Inflammatory Response and Promotes Wound Healing in Diabetic Foot Ulcer Rats via Activating PI3K/AKT Pathway and hTERT

OBJECTIVE: To study the role of miR-138 on the repair of diabetic foot ulcer (DFU) and further to explore its possible mechanism. MATERIALS AND METHODS: miR-138 inhibitor, IGF-1, LY294002 were used in DFU rat mode, and the mRNA expression of miR-138 was detected. HE staining was used to observe the...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Zhao, Xiaodan, Tian, Guichang, Liu, Xiaochao, Gui, Chengyan, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015052/
https://www.ncbi.nlm.nih.gov/pubmed/35444435
http://dx.doi.org/10.2147/DMSO.S359759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015052/
https://www.ncbi.nlm.nih.gov/pubmed/35444435
http://dx.doi.org/10.2147/DMSO.S359759

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