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P2X7 Receptor and Heart Function in a Mouse Model of Systemic Inflammation Due to High Fat Diet

PURPOSE: Low-grade inflammation contributes to heart failure in obesity or type 2 diabetes mellitus. The P2X7 receptor (P2X7R) is a key regulator of several pro-inflammatory responses in multiple tissues and organs; however, its involvement in the onset of heart dysfunction remains unclear. The stud...

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Detalles Bibliográficos
Autores principales: Raggi, Francesco, Rossi, Chiara, Faita, Francesco, Distaso, Mariarosaria, Kusmic, Claudia, Solini, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015053/
https://www.ncbi.nlm.nih.gov/pubmed/35444452
http://dx.doi.org/10.2147/JIR.S356038