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The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle

PURPOSE: Greater muscle fragility is thought to cause the exhaustion of the muscle stem cells during successive degeneration/repair cycles, leading to muscle wasting and weakness in Duchenne muscular dystrophy. Chronic voluntary exercise can partially reduce the susceptibility to contraction induced...

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Detalles Bibliográficos
Autores principales: Monceau, Alexandra, Delacroix, Clément, Lemaitre, Mégane, Revet, Gaelle, Furling, Denis, Agbulut, Onnik, Klein, Arnaud, Ferry, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015141/
https://www.ncbi.nlm.nih.gov/pubmed/35436319
http://dx.doi.org/10.1371/journal.pone.0254274