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Genome-wide DNA hypomethylation drives a more invasive pancreatic cancer phenotype and has predictive occult distant metastasis and prognosis potential

Genome-wide DNA hypomethylation is the most common molecular feature in human cancers associated with chromosomal instability (CIN), which is involved in the mechanisms that regulate pancreatic cancer (PC) metastasis. It was investigated whether genome-wide DNA hypomethylation affects the phenotype...

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Detalles Bibliográficos
Autores principales: Endo, Yuhei, Suzuki, Koichi, Kimura, Yasuaki, Tamaki, Sawako, Aizawa, Hidetoshi, Abe, Iku, Watanabe, Fumiaki, Kato, Takaharu, Saito, Masaaki, Futsuhara, Kazushige, Noda, Hiroshi, Konishi, Fumio, Rikiyama, Toshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015190/
https://www.ncbi.nlm.nih.gov/pubmed/35419613
http://dx.doi.org/10.3892/ijo.2022.5351