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A cAMP-Related Gene Network in Microglia Is Inversely Regulated by Morphine Tolerance and Withdrawal
BACKGROUND: Microglia have recently been implicated in opioid dependence and withdrawal. Mu opioid receptors are expressed in microglia, and microglia form intimate connections with nearby neurons. Accordingly, opioids have both direct (mu opioid receptor mediated) and indirect (neuron interaction m...
Autores principales: | Coffey, Kevin R., Lesiak, Atom J., Marx, Ruby E., Vo, Emily K., Garden, Gwenn A., Neumaier, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015218/ https://www.ncbi.nlm.nih.gov/pubmed/35441155 http://dx.doi.org/10.1016/j.bpsgos.2021.07.011 |
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