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Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti‐SARS‐CoV‐2 Activity

Naturally occurring compounds represent a vast pool of pharmacologically active entities. One of such compounds is andrographolide, which is endowed with many beneficial properties, including the activity against severe acute respiratory syndrome coronavirus type 2 (SARS‐CoV‐2). To initiate a drug r...

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Detalles Bibliográficos
Autores principales: Schulte, Bianca, König, Maria, Escher, Beate I., Wittenburg, Sophie, Proj, Matic, Wolf, Valentina, Lemke, Carina, Schnakenburg, Gregor, Sosič, Izidor, Streeck, Hendrik, Müller, Christa E., Gütschow, Michael, Steinebach, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015489/
https://www.ncbi.nlm.nih.gov/pubmed/35099120
http://dx.doi.org/10.1002/cmdc.202100732