Granzyme B: A Double-Edged Sword in the Response to Influenza Infection in Vaccinated Older Adults

Background: Influenza-specific cytolytic T lymphocytes (CTL) have a critical role in clearing the virus from the lungs, but are poorly stimulated by current inactivated influenza vaccines. Our previous work suggests that granzyme B (GrB) activity predicts protection against laboratory-confirmed infl...

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Detalles Bibliográficos
Autores principales: Verschoor, Chris P., Pawelec, Graham, Haynes, Laura, Loeb, Mark, Andrew, Melissa K., Kuchel, George A., McElhaney, Janet E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015675/
https://www.ncbi.nlm.nih.gov/pubmed/35441156
http://dx.doi.org/10.3389/fragi.2021.753767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015675/
https://www.ncbi.nlm.nih.gov/pubmed/35441156
http://dx.doi.org/10.3389/fragi.2021.753767

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