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TRPM2 deficiency in mice protects against atherosclerosis by inhibiting TRPM2-CD36 inflammatory axis in macrophages

Atherosclerosis is the major cause of ischemic heart disease and stroke, the leading causes of mortality worldwide. The central pathological features of atherosclerosis include macrophage infiltration and foam cell formation. However, the detailed mechanisms regulating these two processes remain unc...

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Detalles Bibliográficos
Autores principales: Zong, Pengyu, Feng, Jianlin, Yue, Zhichao, Yu, Albert S., Vacher, Jean, Jellison, Evan R, Miller, Barbara, Mori, Yasuo, Yue, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015693/
https://www.ncbi.nlm.nih.gov/pubmed/35445217
http://dx.doi.org/10.1038/s44161-022-00027-7