Early B Cell and Plasma Cell Kinetics Upon Treatment Initiation Portend Flares in Systemic Lupus Erythematosus: A Post-Hoc Analysis of Three Phase III Clinical Trials of Belimumab

OBJECTIVE: To investigate changes in B cell subsets in relation to disease flares upon initiation of standard therapy (ST) plus belimumab or placebo in patients with systemic lupus erythematosus (SLE). PATIENTS AND METHODS: Using data from the BLISS-76, BLISS-SC and BLISS Northeast Asia trials, we i...

Descripción completa

Detalles Bibliográficos
Autores principales: Parodis, Ioannis, Gomez, Alvaro, Chow, Jun Weng, Borg, Alexander, Lindblom, Julius, Gatto, Mariele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015703/
https://www.ncbi.nlm.nih.gov/pubmed/35444642
http://dx.doi.org/10.3389/fimmu.2022.796508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015703/
https://www.ncbi.nlm.nih.gov/pubmed/35444642
http://dx.doi.org/10.3389/fimmu.2022.796508

Ejemplares similares