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Early B Cell and Plasma Cell Kinetics Upon Treatment Initiation Portend Flares in Systemic Lupus Erythematosus: A Post-Hoc Analysis of Three Phase III Clinical Trials of Belimumab

OBJECTIVE: To investigate changes in B cell subsets in relation to disease flares upon initiation of standard therapy (ST) plus belimumab or placebo in patients with systemic lupus erythematosus (SLE). PATIENTS AND METHODS: Using data from the BLISS-76, BLISS-SC and BLISS Northeast Asia trials, we i...

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Detalles Bibliográficos
Autores principales:	Parodis, Ioannis, Gomez, Alvaro, Chow, Jun Weng, Borg, Alexander, Lindblom, Julius, Gatto, Mariele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015703/ https://www.ncbi.nlm.nih.gov/pubmed/35444642 http://dx.doi.org/10.3389/fimmu.2022.796508

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