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Platelets fine-tune effector responses of naïve CD4(+) T cells via platelet factor 4-regulated transforming growth factor β signaling
BACKGROUND AND AIM: Platelets are an able regulator of CD4(+) T cell immunity. Herein, the mechanisms underlying platelet-regulated effector responses of naïve CD4(+) T (Tn) cells were investigated. METHODS: Platelet–Tn cell co-cultures of human cells, genetically modified murine models, and high-th...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016031/ https://www.ncbi.nlm.nih.gov/pubmed/35437611 http://dx.doi.org/10.1007/s00018-022-04279-1 |