Platelets fine-tune effector responses of naïve CD4(+) T cells via platelet factor 4-regulated transforming growth factor β signaling

BACKGROUND AND AIM: Platelets are an able regulator of CD4(+) T cell immunity. Herein, the mechanisms underlying platelet-regulated effector responses of naïve CD4(+) T (Tn) cells were investigated. METHODS: Platelet–Tn cell co-cultures of human cells, genetically modified murine models, and high-th...

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Detalles Bibliográficos
Autores principales: Min, Yanan, Hao, Long, Liu, Xinguang, Tan, Shuai, Song, Hui, Ni, Hao, Sheng, Zi, Jooss, Natalie, Liu, Xuena, Malmström, Rickard E., Sun, Yang, Liu, Jianguo, Tang, Hua, Zhang, Hao, Ma, Chunhong, Peng, Jun, Hou, Ming, Li, Nailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016031/
https://www.ncbi.nlm.nih.gov/pubmed/35437611
http://dx.doi.org/10.1007/s00018-022-04279-1

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