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Enzymatic Degradation of Cortical Perineuronal Nets Reverses GABAergic Interneuron Maturation

Perineuronal nets (PNNs) are specialised extracellular matrix structures which preferentially enwrap fast-spiking (FS) parvalbumin interneurons and have diverse roles in the cortex. PNN maturation coincides with closure of the critical period of cortical plasticity. We have previously demonstrated t...

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Detalles Bibliográficos
Autores principales: Willis, Ashleigh, Pratt, Judith A., Morris, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016038/
https://www.ncbi.nlm.nih.gov/pubmed/35233718
http://dx.doi.org/10.1007/s12035-022-02772-z